University of Maryland School of Medicine
This TMA is comprised of 104 retrospective peritoneal malignant mesothelioma cases and turmor cores from patients with 91% of surgical resection performed at the University of Maryland Medical Center (UMMC) from 2006-2016.The predominant histological type is epithelial or epithelioid in 93% of cases. There are positive history of smoking in 31% of cases and history of asbestos exposure in 29 % of cases. All cases were reviewed microscopically by pathologists and tissue cores were selected based on variation in histologic type, nucleolar grade, level of invasion, and degree of inflammation. A code was assigned to each core at the time of microscopic review using the latest histologic evaluation standards. Two TMA’s were ultimately prepared to include all cases with sufficient size core extraction. The TMA’s will be stored in the Pathology Biorepository Shared Service (PBSS) core facility at the University of Maryland School of Medicine (UMB) for future requests made by the NMVB team.