TOTAL TMA SUMMARY
 See below for a summary of the 9 TMAs that the National Mesothelioma Virtual Bank (NMVB) has collected. For more information, please contact us

University of Pittsburgh

 TMA 1 

TMA has been designed to facilitate identification of markers differentially expressed in primary mesothelioma lesions as well as metastatic lesions. Samples from 40 patients have been incorporated: 36 patients have tissue cores from the primary lesion only, 3 patients have tissue cores from a metastatic lesion only, and 1 patient has tissue cores from both the primary and metastatic lesions. Of the patients with available clinical annotation, 97% are male and 3% are female, and racial breakdown is as follows: 57% white, 3% black, and 39% unknown. Pathologic site and histologic type for annotated cases is shown.

Histologic TypeCases
Biphasic10
Epithelial/Epitheliod20
Sarcomatoid3
Multicystic1
Papillary2
Benign Fibrous2
Fibrocystic1
Desmoplastic1
Benign4
Malignant36
Primary36
Metastatic3
Primary/Metastatic1
Pathologic SiteCases
Pleura Not Specified25
Peritoneum13
Other2
 
 
 
Histologic TypeCases
Epithelial/Epitheliod90%
Sarcomatoid10%
Pathologic SiteCases
Pleura Right50%
Pleura Left35.7%
Pleura80%
Pleura Not Specified12.5%
Other20%
 
 
 

TMA 2  

TMA has been designed to facilitate identification of markers differentially expressed in primary mesothelioma lesions as well as metastatic lesions. Samples from 12 patients have been incorporated. Pathologic site and histologic type for annotated cases is shown.

Histologic TypeCases
Biphasic9
Epithelial/Epitheliod39
Sarcomatoid5
Multicystic0
Papillary0
Benign Fibrous0
Fibrocystic0
Desmoplastic1
  
  
  
  
  
Pathologic SiteCases
Pleura Not Specified49
Peritoneum3
Other2
 
 
 

TMA 3

TMA has been designed to facilitate identification of markers differentially expressed in primary mesothelioma lesions as well as metastatic lesions. Samples from 9 patients have been incorporated. Pathologic site and histologic type for annotated cases is shown.

Histologic TypeCases
Biphasic9
Epithelial/Epitheliod39
Sarcomatoid5
Multicystic0
Papillary0
Benign Fibrous0
Fibrocystic0
Desmoplastic1
  
  
  
  
  
Pathologic SiteCases
Pleura Not Specified49
Peritoneum3
Other2
 
 
 

TMA 4

TMA has been designed to facilitate identification of markers differentially expressed in primary mesothelioma lesions as well as metastatic lesions. Samples from 30 patients have been incorporated. Pathologic site and histologic type for annotated cases is shown.

Histologic TypeCases
Biphasic9
Epithelial/Epitheliod39
Sarcomatoid5
Multicystic0
Papillary0
Benign Fibrous0
Fibrocystic0
Desmoplastic1
  
  
  
  
  
Pathologic SiteCases
Pleura Not Specified49
Peritoneum3
Other2
 
 
 

Roswell Park Comprehensive Cancer Center

TMA 1

TMA has been designed to facilitate identification of markers differentially expressed in primary mesothelioma lesions as well as metastatic lesions. Samples from 56 patients have been incorporated. Pathologic site and histologic type for annotated cases is shown.

Histologic TypeCases
Biphasic10
Epithelial/Epitheliod33
Sarcomatoid3
Multicystic1
Papillary1
Benign Fibrous0
Fibrocystic0
Desmoplastic0
Benign0
Malignant56
Primary24
Metastatic3
Primary/Metastatic 
Pathologic SiteCases
Pleura Not Specified37
Peritoneum9
Other10

University of Maryland

TMA 1 and 2

TMA has been designed to facilitate identification of markers differentially expressed in peritoneal samples. Samples from 105 patients have been incorporated. Pathologic site and histologic type for annotated cases is shown.

Histologic TypeCases
Biphasic2
Epithelial/Epitheliod97
Sarcomatoid5
Multicystic0
Papillary0
Benign Fibrous0
Fibrocystic0
Desmoplastic0
Benign0
Malignant104
Primary105
Metastatic0
Primary/Metastatic 
Pathologic SiteCases
Pleura Not Specified0
Peritoneum105
Other0

New York University Langone Medical Center 

TMA 1

An intermediate-density tissue microarray for testing biomarkers strongly associated with mesothelioma. This TMA contains tumor samples from malignant mesothelioma cases. All of the cases were obtained from the NYU Site of the National Mesothelioma Virtual Bank, which were collected with institutional review board approval. 

Histologic TypeCases
Biphasic8
Epithelial/Epitheliod24
Sarcomatoid2
Multicystic1
Papillary0
Benign Fibrous0
Fibrocystic0
Desmoplastic2
Benign0
Malignant36
Primary0
Metastatic0
Primary/Metastatic 
Pathologic SiteCases
Pleura Not Specified31
Peritoneum1
Other5