TMA has been designed to facilitate identification of markers differentially expressed in primary mesothelioma lesions as well as metastatic lesions. Samples from 40 patients have been incorporated: 36 patients have tissue cores from the primary lesion only, 3 patients have tissue cores from a metastatic lesion only, and 1 patient has tissue cores from both the primary and metastatic lesions. Of the patients with available clinical annotation, 97% are male and 3% are female, and racial breakdown is as follows: 57% white, 3% black, and 39% unknown. Pathologic site and histologic type for annotated cases is shown.
Histologic Type | Cases |
---|---|
Biphasic | 10 |
Epithelial/Epitheliod | 20 |
Sarcomatoid | 3 |
Multicystic | 1 |
Papillary | 2 |
Benign Fibrous | 2 |
Fibrocystic | 1 |
Desmoplastic | 1 |
Benign | 4 |
Malignant | 36 |
Primary | 36 |
Metastatic | 3 |
Primary/Metastatic | 1 |
Pathologic Site | Cases |
---|---|
Pleura Not Specified | 25 |
Peritoneum | 13 |
Other | 2 |
Supporting Documents |
---|
University of Pittsburgh TMA-1 Map: Map |
University of Pittsburgh TMA-1 Whole Slide Image: Whole Slide Image |
University of Pennsylvania
The TMA has been designed to facilitate identification of markers differentially expressed in primary mesothelioma lesions as well as metastatic lesions. Samples from 10 patients have been incorporated: 4 patients have tissue cores from the primary lesion only, 5 patients have tissue cores from the primary lesion and normal tissue, and 1 patient has tissue cores from the normal tissue, primary and metastatic lesions. Of the patients with available clinical annotation, 60% are male and 40% are female, and racial breakdown is as follows: 100% white.
Histologic Type | Cases |
---|---|
Epithelial/Epitheliod | 90% |
Sarcomatoid | 10% |
Pathologic Site | Cases |
---|---|
Pleura Right | 50% |
Pleura Left | 35.7% |
Pleura | 80% |
Pleura Not Specified | 12.5% |
Other | 20% |
Supporting Documents |
---|
University of Pennsylvania TMA-1 Map Microsoft Excel file: Map |
University of Pennsylvania TMA-1 Whole Slide Image: Whole Slide Image |
Datasheet: Available on request
XML: Available on Request