TMA 1

TMA has been designed to facilitate identification of markers differentially expressed in primary mesothelioma lesions as well as metastatic lesions. Samples from 40 patients have been incorporated: 36 patients have tissue cores from the primary lesion only, 3 patients have tissue cores from a metastatic lesion only, and 1 patient has tissue cores from both the primary and metastatic lesions. Of the patients with available clinical annotation, 97% are male and 3% are female, and racial breakdown is as follows: 57% white, 3% black, and 39% unknown. Pathologic site and histologic type for annotated cases is shown.

Histologic TypeCases
Biphasic10
Epithelial/Epitheliod20
Sarcomatoid3
Multicystic1
Papillary2
Benign Fibrous2
Fibrocystic1
Desmoplastic1
Benign4
Malignant36
Primary36
Metastatic3
Primary/Metastatic1
Pathologic SiteCases
Pleura Not Specified25
Peritoneum13
Other2
Supporting Documents
University of Pittsburgh TMA-1 Map: Map
University of Pittsburgh TMA-1 Whole Slide Image: Whole Slide Image
Histologic TypeCases
Epithelial/Epitheliod90%
Sarcomatoid10%
Pathologic SiteCases
Pleura Right50%
Pleura Left35.7%
Pleura80%
Pleura Not Specified12.5%
Other20%
Supporting Documents
University of Pennsylvania TMA-1 Map Microsoft Excel file: Map
University of Pennsylvania TMA-1 Whole Slide Image: Whole Slide Image